Transient muscle paralysis degrades bone via rapid osteoclastogenesis
نویسندگان
چکیده
منابع مشابه
The effects of masseter muscle paralysis on facial bone growth.
BACKGROUND Understanding the effects of muscle function on facial bone growth may help us treat children with facial anomalies. Facial bone growth is known to be a result of both genetic and epigenetic influences. One of the main epigenetic factors controlling growth is thought to be muscle action. The purpose of this study was to establish a model of single facial muscle paralysis and to ident...
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Fibrous dysplasia of bone FD is caused by somatic mutations of the GNAS1. Here, patterns of osteoclastogenesis and bone resorption reflect not only the.FIBROUS DYSPLASIA FD is a sporadic developmental disorder characterized by. Biochemical indices of bone turnover are usually high particularly serum. Osteoclasts within the lesions is slightly higher than normal and the number of.Introduction: F...
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Paralysis of the soleus muscle in newborn rats causes a large proportion of motoneurons to die by 10 weeks of age. However, all of these neurons are still present at three to four weeks of age. We have previously shown that although nerve injury at five days does not result in any motoneuron death, it does render these neurons susceptible to the toxic effects of the glutamate agonist N-methyl-D...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2011
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.11-196642